Table 3 Chemotherapy responses of tumors in human patients and PDX mice.

From: In vivo label-free optical signatures of chemotherapy response in human pancreatic ductal adenocarcinoma patient-derived xenografts

Patient #

Neoadjuvant therapy received by human patient

Response in human patient

Response in corresponding PDX mice

1

5-FU based regimen like FIRINOX

Responsive to 5-FU based regimen

Responsive to FIRINOX

2

Gem/NabP

Resistant to Gem/NabP

Resistant to FIRNOX (Not received by the patient)

3

Gem/NabP

Responsive to Gem/NabP

Resistant to FIRNOX (Not received by the patient)

Responsive to Gem/NabP

  1. Responsiveness or resistance to neoadjuvant chemotherapy received by human patients prior to tumor removal is indicated. After tumor was removed, the response of that tumor was recorded in PDX mice to either FIRINOX or Gem/NabP.
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