Fig. 5: Anti IL-17A antibodies bind IL-17A with high specificity. | Communications Biology

Fig. 5: Anti IL-17A antibodies bind IL-17A with high specificity.

From: “Redirecting an anti-IL-1β antibody to bind a new, unrelated and computationally predicted epitope on hIL-17A”

Fig. 5: Anti IL-17A antibodies bind IL-17A with high specificity.

a SPR binding kinetics of BDG11.003, BDG 11.004, BDG, 11.006 and BDG11.007 to human IL-17A. b. Polyspecificity ELISA binding assay of BDG11.001, BDG11.003, BDG11.004 (upper panel), BDG11.006 and BDG11.007 (lower pane). Anti hIL-17A antibodies show to have specific binding to hIL-17A and no binding to KLH, insulin, LPS, ssDNA, hIL-2, hTNFR2, and BSA. Positive controls for hIL-2, hTNFR2, and hIL-17A were anti-IL-2 antibody, anti-TNFR2 antibody, and anti-IL-17A antibody respectively. Analysis was done in GraphPad Prism 9 using 2-way ANOVA. Data are n = 2 technical replicates.

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