Fig. 6: Change in cytokine expression profiles in LPS-stimulated THP-1 macrophages treated with citrus extracts of different biotransformation level. | Communications Biology

Fig. 6: Change in cytokine expression profiles in LPS-stimulated THP-1 macrophages treated with citrus extracts of different biotransformation level.

From: Combined acid hydrolysis and fermentation improves bioactivity of citrus flavonoids in vitro and in vivo

Fig. 6

a Representative images of cytokine arrays incubated with supernatants of differentiated THP-1 macrophages treated with aqueous citrus extract (AQE) or fermented citric acid hydrolyzed citrus extract (FermCAE) under lipopolysaccharide (LPS) challenge. Cytokines expressed are presented as duplicate spots. Important cytokines are outlined and marked with numbers. The corresponding spot intensities (stated as arbitrary units, A.U.) of these analytes are presented in b. Data of technical duplicates are shown. c Heat map of 105 cytokines with mean spot intensities in a color range from white (low level) to blue (high level).

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