Fig. 5: Genome-wide dynamic patterns of DNA methylation during postnatal muscle growth.
From: Genome-wide epigenetic dynamics during postnatal skeletal muscle growth in Hu sheep
a Box plot summarizing mean genome-wide methylation at the sample level. b Proportion of three types of methylated cytosine contexts across four stages: CHG, CHH, and CpG. c Box plot summarizing mean genome-wide methylation at the chromosome level. “*” means a significant difference (P < 0.05, adjusted by FDR) between the two stages. Violin plot for methylation of high methylation domains (HMD, d) and low methylation regions (LMR, e). The line in the LMR violin plot represents the median expression of genes with LMR (right y axis). Groups showing a significant difference were labeled with exact P value. f Line plot exhibiting mean methylation of flank sequence (DMR ± 500 bp) and DMR across four stages. Boxes or violin represent 25th to 75th percentile and whiskers represent minimum-maximum. Horizontal lines and points within boxes represent the median and mean respectively (n = 3). DMR differential methylation regions, HMD high methylation domains, LMR low methylation regions.
