Fig. 9: The effects of epigenetic modification on postnatal muscle fiber transformation.
From: Genome-wide epigenetic dynamics during postnatal skeletal muscle growth in Hu sheep
a Muscle fiber types distribution. Representative images of fiber types at D3 and M3 are shown. Scale bar: 130 µm. b Quantification of the proportion of the slow-twitch fibers at D3 and M3 (n = 6), P value = 0.01. c Genes with significant positive correlation and negative correlation with the proportion of the slow-twitch fibers. x and y axes, respectively represent gene expression in D3 and Spearman correlation efficiency (rho). d GO items for metabolic genes in (c). e KEGG items for metabolic genes in (c). f TF-targets networks of IDR (IDR network) based on metabolic genes and transcription factors in Fig. 4c. g TF-targets networks of LMR (LMR network) based on metabolic genes and transcription factors in Fig. 6c. Red targets are the metabolic genes in (c) and their GO items in (d) is in the lower right corner. Error bars represent mean values ± SD. IDR irreproducible discovery rate, LMR low methylation regions, SD standard deviation.
