Fig. 5: A ketogenic diet counteracts metabolic changes induced by SARS-CoV-2 infection.
From: A ketogenic diet can mitigate SARS-CoV-2 induced systemic reprogramming and inflammation
a Biological classification of total altered metabolites in serum, heart, liver and kidney (n = 5/group biologically independent samples, p < 0.05 and FC > |1.5 | ); (b) log2FC of metabolites showing significant changes in paired analysis of CD-SARS-CoV-2 vs CD or KD-SARS-CoV-2 vs KD (indicated as CD and KD, respectively, n = 5/group biologically independent samples, p < 0.05 and FC > |1 | ); (c) heatmap of log2 intensities for significant metabolites in KD-SARS-CoV-2 vs CD-SARS-CoV-2 mice for serum, kidney, and liver (n = 5/group) biologically independent samples, p < 0.05 and FC > |1 | , no significant features in the heart. Metabolite abbreviations are reported in Supplementary Data 8.
