Fig. 8: Activity of CaV1.2 channels is reduced in KV2.1S590A female but not male arterial myocytes. | Communications Biology

Fig. 8: Activity of CaV1.2 channels is reduced in KV2.1S590A female but not male arterial myocytes.

From: The formation of KV2.1 macro-clusters is required for sex-specific differences in L-type CaV1.2 clustering and function in arterial myocytes

Fig. 8: Activity of CaV1.2 channels is reduced in KV2.1S590A female but not male arterial myocytes.The alternative text for this image may have been generated using AI.

Representative sparklet traces from KV2.1WT male (a) and KV2.1S590A male (b) myocytes. κ values are shown above each trace. c nPs values from low and high activity sites in male myocytes. d Coupling coefficient values (κ) from male myocytes. e Sparklet sites per cell from male myocytes (n = 16 KV2.1WT and 9 KV2.1S590A male myocytes). Representative sparklet traces from KV2.1WT female (f) and KV2.1S590A female (g) myocytes. h nPs values from low and high activity sites in female myocytes. i Coupling coefficient values (κ) from female myocytes. j Sparklet sites per cell from female myocytes (n = 16 KV2.1WT and 10 KV2.1S590A female myocytes. *P < 0.05, **P < 0.01. Error bars indicate mean ± SEM.

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