Fig. 7: Efficacy of cleavable chimeric peptide R7 in the mice challenged wiht LPS. | Communications Biology

Fig. 7: Efficacy of cleavable chimeric peptide R7 in the mice challenged wiht LPS.

From: A cleavable chimeric peptide with targeting and killing domains enhances LPS neutralization and antibacterial properties against multi-drug resistant E. coli

Fig. 7

a Survival of mice. Mice were intraperitoneally injected with different peptides (7 μmol/kg) at 0 h (five mice/group), followed by injection with LPS (13.5 mg/kg of body weight) at 6 h. Survival was recorded for 7 days. Two biological replicates were done. b–f Effects of L7 and R7 on cytokines (b–e) and the IAP levels (f). The results are given as the mean ± SD of three independent experiments. Different lower-case letters indicate a significant difference between the two groups (p < 0.05).

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