Fig. 5: Effects of compounds 1 on the pantothenate transport-activity of ECF transporter ECF-PanT.
From: Identification of inhibitors targeting the energy-coupling factor (ECF) transporters
a Schematic representation of uptake assay. b Pantothenate uptake by ECF PanT in proteoliposomes filled with 5 mM of MgATP (black), 5 mM of MgADP (purple), 5 mM MgATP plus 5 mM of compound 1 (red), and a final DMSO concentrations of 5% (v/v). The blue curve represents proteoliposomes filled with 5 mM MgATP and no DMSO. The error bars represent the standard deviation of three independent measurements, except for the data in panel B, where they represent the spread of the data from two independent measurements.
