Table 1 Quantification of apoptotic cells in the cortical wall of fetuses of the control and T. gondii infection groups.

From: Reduced neural progenitor cell count and cortical neurogenesis in guinea pigs congenitally infected with Toxoplasma gondii

Fetus no.

Group

Gestation day

Number of apoptosisa

Cortical zoneb

Mean ± SEMc

4A

Infected

40

1

SVZ

0.6 ± 0.4

4B

Infected

40

0

 

5A

Infected

40

2

SVZ

5B

Infected

40

0

 

5D

Infected

40

0

 

7A

Infected

48

0

 

0.4 ± 0.1633

7B

Infected

48

1

SVZ

8A

Infected

48

1

SVZ

8B

Infected

48

0

 

8C

Infected

48

0

 

9A

Infected

48

1

CP

9B

Infected

48

0

 

9C

Infected

48

0

 

9D

Infected

48

0

 

9E

Infected

48

1

CP

10A

Control

40

0

 

0.7143 ± 0.4738

10B

Control

40

0

 

11A

Control

40

0

 

11B

Control

40

0

 

11C

Control

40

2

SVZ

12A

Control

40

0

 

12B

Control

40

3

SVZ

13A

Control

48

0

 

0

14A

Control

48

0

 

14B

Control

48

0

 

15A

Control

48

0

 

15B

Control

48

0

 
  1. SVZ subventricular zone, CP cortical plate.
  2. aNumber of apoptotic cells identified by immunohistochemistry for activated caspase 3 and quantified in the cortical wall per 100 µm ventricular surface.
  3. bCortical zone in which apoptotic cells were detected.
  4. cMean ± SEM of the number of apoptotic cells quantified in the entire cortical wall per 100 µm ventricular surface of the infection and control groups. For the infection groups, data are from all guinea pig fetal brains with Ct value below 35 as determined by qPCR for T. gondii. Mann–Whitney test was used to compare the number of apoptotic cells quantified in the cortical wall between the control and infection group; P (gestation day 40) = 0.5758, P (gestation day 48) = 0.1538).