Fig. 5: Depleted gut microbiota remarkably abolishes the renal protective of HP against c-BSA induced MN in rats. | Communications Biology

Fig. 5: Depleted gut microbiota remarkably abolishes the renal protective of HP against c-BSA induced MN in rats.

From: Hydrangea paniculata coumarins attenuate experimental membranous nephritis by bidirectional interactions with the gut microbiota

Fig. 5

a Illustration of experimental design to treat MN rats whose gut microbiota have been depleted by ABX drinking; (n = 10). b Renal function, albuminuria, serum cholesterol in different groups; (n = 10). c Reduction of IgG deposition by HP was partially diminished by gut microbiota depletion via immunofluorescence. *P < 0.05, **P < 0.01, tested by one-way ANOVA test. (White bars = 20 µm). Bar graphs are means ± SD.

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