Fig. 2: Results of assembling predicted domain structures. | Communications Biology

Fig. 2: Results of assembling predicted domain structures.

From: Multi-domain and complex protein structure prediction using inter-domain interactions from deep learning

Fig. 2

a Average TM-score over 219 multi-domain proteins for DeepAssembly and AlphaFold2. The y-axis on the right represents the full-chain RMSD of proteins. Error bars are 95% confidence intervals. b Head-to-head comparison of the TM-scores (left panel) and RMSDs (right panel) on each test case between DeepAssembly and AlphaFold2. “n” refers to the number of points on either side of the diagonal. c Histogram of backbone RMSD for full-chain models by DeepAssembly and AlphaFold2. d TM-score comparisons between AlphaFold2 full-length model and its single domain parts (AF2 domain) on the corresponding proteins of the models predicted by AlphaFold2 with TM-score less than each cutoff. e TM-score comparisons between DeepAssembly and AlphaFold2 on the corresponding proteins of the models predicted by AlphaFold2 with TM-score less than each cutoff. “cutoff” refers to a TM-score value on the x-axis, which reflects a TM-score interval less than this value.

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