Fig. 6: No Krt5+ progenitor cells proliferate in CoV2-infected nonhuman primates or human patients.
From: COVID-19 and influenza infections mediate distinct pulmonary cellular and transcriptomic changes
a Krt5+ progenitor cells (green) are normally identified in the basal layer of proximal conducting airways as seen in the SARS-CoV-2 infected NHP (top right). Following RSV infection in nonhuman primate (n = 1), there is proliferation of Krt5+ cells within airways and the adjacent pulmonary parenchyma which is not observed in SARS-CoV-2-infected nonhuman primates (n = 4). b Adult human COVID patient (patient 1) exhibits a similar reaction pattern to SARS-CoV-2 infected nonhuman primates with Krt5+ cells largely restricted to airways and rarely found within the pulmonary parenchyma.
