Fig. 2: Metabolic profiling of RelQ cells. | Communications Biology

Fig. 2: Metabolic profiling of RelQ cells.

From: ppGpp accumulation reduces the expression of the global nitrogen homeostasis-modulating NtcA regulon by affecting 2-oxoglutarate levels

Fig. 2

Time-course changes in intracellular metabolite pool sizes of RelQ cells with (●, RelQ-ox) or without (○, RelQ) IPTG addition after 72 h of initial culture in the presence of sodium nitrate. Statistical significance between each sampling point of RelQ-ox and RelQ cells was determined using Student’s t test (**p < 0.01, *p < 0.05). Black and gray arrows represent direct and indirect reaction, respectively. Abbreviations: G1P, glucose 1-phosphate; S7P, sedoheptulose 7-phosphate; R5P, Ribose 5-phosphate; FBP, fructose 1,6-bisphosphate; Ru5P, ribulose 5-phosphate; F6P, fructose 6-phosphate; RuBP, ribulose 1,5-bisphosphate; PEP, phosphoenolpyruvate; 2PGA, 2-phosphoglycerate; 3PGA, 3-phosphoglycerate; 2-OG, 2-oxoglutarate.

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