Fig. 4: Performance evaluation on human MTG using all methods.
From: STEM enables mapping of single-cell and spatial transcriptomics data with transfer learning
a The overall reconstructed spatial distribution of single cells obtained by STEM. The six subplots show the spatial distribution of cells in L1-L6 groups. These groups were determined based on tissue dissection information. b Comparison of cortical-depth distribution of cell groups between different methods. The enhanced boxplot in various colors displays the cortical-depth distribution of different single cell groups. The dashed lines indicate the boundaries of layer regions given by ST data. The horizontal bar inside the box represents the median of all values. Each edge of the box represents the half percentiles of the rest data, in other words, splitting the rest data into two halves. c Neighborhood enrichment analysis between SC and ST data using all methods. The x axis represents regions in the ST data while the y axis represents SC excitatory neurons from different dissection layers. The score is row-normalized, and the red color indicates a higher neighborhood score. Bold squares represent areas where high scores are expected.
