Fig. 3: Summary of assay development in 20 mouse organs and tissues. | Communications Biology

Fig. 3: Summary of assay development in 20 mouse organs and tissues.

From: Multiple reaction monitoring assays for large-scale quantitation of proteins from 20 mouse organs and tissues

Fig. 3: Summary of assay development in 20 mouse organs and tissues.The alternative text for this image may have been generated using AI.

a shows the number of peptide assays for which a response curve was successfully characterized and assay variability was < 20% for each sample type. Number of passing assays are indicated in blue and failed assays by yellow b shows the number of unique proteins with developed assays in each organ or tissue, ranging from approximately 100 proteins in white adipose tissue to > 600 proteins in plasma and brain. Bars are shaded by the proportion of assays for which the endogenous protein was within the assay range in normal, healthy samples. The overlap of assays across sample types is shown in c, where 637 of the developed assays are unique to a single organ or tissue, and the remaining 1481 (70%) were validated in more than one sample type.

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