Fig. 1: Diversities of fecal microbiota, differential bacterial species and venn diagram of all differential species. | Communications Biology

Fig. 1: Diversities of fecal microbiota, differential bacterial species and venn diagram of all differential species.

From: Multi-kingdom microbial signatures in excess body weight colorectal cancer based on global metagenomic analysis

Fig. 1

a Boxplot of alpha diversities measured by Shannon index of lean-CRC, EBW-CRC, lean-CTR and EBW-CTR groups. (n = 123, 135, 140 and 123 for lean-CRC, EBW-CRC, lean-CTR and EBW-CTR, respectively). Statistical differences were evaluated by Wilcoxon rank sum test. b Beta diversities of the discovery cohorts were assessed by principal coordinate analysis (PCoA) based on Bray-Curtis dissimilarity. P values and R-square values of beta diversity based on Bray–Curtis distance were calculated with PERMANOVA by 999 permutations (two-sided test). c, d Phylogenetic tree of the differential bacterial species in EBW-CRC (c, 60 species) and lean-CRC (d, 50 species). The outer circles are marked as significantly differential species (FDR-corrected P < 0.05) in each cohort and in the meta-analysis (meta-ring) with red for increased abundance and blue for decreased abundance. e Venn diagram of all differential species in EBW- and lean-CRC identified from the meta-analysis of the discovery cohorts.

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