Fig. 5: The associations between differential species and differential pathways.

Heatmaps show the correlation coefficients of association between differential species and pathways in EBW-CRC a and lean-CRC b, respectively. Color red represents for positive association and blue for negative association. P values, FDR-corrected P values, and correlation coefficients were computed via Hierarchical All-against-All association testing. Asterisks indicate statistical significance (*, FDR-corrected P ≤ 0.05; **, FDR-corrected P ≤ 0.01; ***, FDR-corrected P ≤ 0.001).