Fig. 1: Single cell RNA-seq unveiled a subset of T/B biphenotypic lymphocytes in mice. | Communications Biology

Fig. 1: Single cell RNA-seq unveiled a subset of T/B biphenotypic lymphocytes in mice.

From: A biphenotypic lymphocyte subset displays both T- and B-cell functionalities

Fig. 1

a Lymphocytes isolated from mouse BM (bone marrow), LN (lymph nodes) and B (blood) were firstly purified using a BD FACSAria™ III Sorter and then subjected to single cell RNA and immune repertoire sequencing. 1°: The first round of experiment; 2°: The second round of experiment. b Lymphocytes isolated from mouse were visualized by either tissue types (left) or cell subsets (right) with UMAP. c Proportional contribution of the three tissues (B, BM, and LN) to T/B clusters. The apparatus illustration was obtained from the official website of 10× Genomics (https://www.10xgenomics.com/instruments/chromium-x-series).

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