Table 3 Biological pathways associated with differential methylation in DLB.

From: Differential methylation analysis in neuropathologically confirmed dementia with Lewy bodies

ID

Pathway

Source

No. Genes

P value

GO:0048583

regulation of response to stimulus

GO:BP

18

4.57E-03

GO:0051716

cellular response to stimulus

GO:BP

20

3.11E-02

GO:0014069

postsynaptic density

GO:CC

5

2.74E-02

GO:0031253

cell projection membrane

GO:CC

5

3.27E-02

GO:0032279

asymmetric synapse

GO:CC

5

3.14E-02

GO:0099572

postsynaptic specialization

GO:CC

5

3.82E-02

GO:0031982

vesicle

GO:CC

6

4.85E-02

GO:0098984

neuron to neuron synapse

GO:CC

5

4.90E-02

TF:M12593

Factor: CTCF; motif: NNRSYGCCMCCTGSTGGCCN

TF

29

1.11E-03

TF:M00918

Factor: E2F; motif: TTTSGCGSG

TF

14

3.49E-02

  1. No. Genes number of genes, GO Gene Ontology, BP Biological Process, CC Cellular Component, TF TRANSFACT.
  2. P value refers to Bonferroni corrected p value.