Fig. 1: Structure of a tetrameric septin complex.

A Crystal structure of the yeast septin complex with a tetramer in the asymmetric unit. The interfaces are indicated and the nucleotides are displayed in ball-and-stick presentation. Filaments with non-physiological Shs1-Cdc10 interfaces are present in the crystal and can be generated by symmetry operations. B Subunit Cdc3 with annotated structural key features. Sheets and helices are numbered according to the classical G-domain numbering of Ras-like proteins. SUE: septin unique element; Tr: trans-loop; PB: poly-basic motif; PAR: poly-acidic region. The GDP is shown as ball-and-stick presentation. C Consensus sequences of selected structural features, created with WebLogo⁵⁰. Alignments were fetched from Phylome-DB⁵¹.