Fig. 2: Higher temperature led to upregulated expression of Trpv4 in Leydig cells.

a qRT-PCR analysis of Trp family genes in the testes. Values are the mean ± SEM (n = 3). **p < 0.01 and *p < 0.05 compared with the 29 °C testis. b In situ hybridization of Trpv4 in testes. c Double in situ hybridization of Trpv4 (blue) and Insl3 (yellow). The insets were magnified in the bottom rows. Scale bars are 20 μm (b and c: high magnification) and 50 μm (c: low magnification).