Fig. 2: Gene Ontology supports the view that KD alters synaptic plasticity in APP/PS1 mice. | Communications Biology

Fig. 2: Gene Ontology supports the view that KD alters synaptic plasticity in APP/PS1 mice.

From: Ketogenic diet and BHB rescue the fall of long-term potentiation in an Alzheimer’s mouse model and stimulates synaptic plasticity pathway enzymes

Fig. 2

a Volcano plot of differentially expressed genes (DEGs) induced by KD. Upregulated genes are shown in green, while downregulated genes are shown in red. Genes with log2FC greater than 2 or lower than −2 or the most significant are also labeled. The dimension of dots reflects the logCPM (logarithm of counts per million reads). b Ingenuity Pathway Analysis of genes influenced by diet. Canonical pathways with absolute z-score greater than 2 and −log p-value > 1.3 are reported in green, while dimensions of dots reflect FDR values as indicated in figure.

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