Fig. 6: The absence of the PCT/CT transcript of the CALCA gene alleviates ACLT-induced synovitis.

a Representative images of femoral synovitis evidenced by synovial hypertrophy and hyperplasia (black arrows) in indicated groups stained with BIC (scale bar = left column 200 μm; right column 50 μm). b Synovitis scoring of the total joint, femoral and tibia compartments at the indicated time points. n = 7,8 biologically independent animals as indicated per group and time point. Ordinary one-way ANOVA was used to determine statistical differences. Box plots represent median with minimum and maximum whiskers. *P < 0.05.