Table 1 Non-exhaustive list of microscopy vendors offering TPE microscopy instrumentation highlighting unique features of each

From: More than double the fun with two-photon excitation microscopy

Vendor

Model(s)

Notable features

3i

VIVO Multiphoton

- Very flexible, customisable platform

- Integrated adaptive optics

Bruker

Ultima Series

- Rotating nosepiece

- Remote focussing

Leica Microsystems

SP8 / Stellaris 8 DIVE

- Fully integrated with confocal LSM

- Up to 4 non-descanned detectors

- FLIM acquisition and analysis packages

Nikon

AX R MP

- Resonance scanner (720 fps at 512 × 16 pixels)

- Tilting nosepiece

- Array detector for increased SNR and resolution (NSPARC)

Olympus

FVMPE-RS

- Broad transmission 400 nm–1600 nm

- Multichannel IR excitation

Prospective Instruments

MPX

- Compact and fully integrated system

- FLIM capable

Sutter Instruments

MOM/DF Scope

- Moveable objective

- Collection of emitted light above & below the sample for increased detection efficiency/SNR

Thorlabs

Bergamo II Series

Mesoscope

- Flexible geometry with rotating body

- Extended depth of field using Bessel beam

- Dual plane imaging

- Remote focussing

- TPE random access modality

Zeiss

NLO module for LSM 980 (nonlinear optical microscopy)

- Integrated with LSM platform

- Combination with airyscan offers increased resolution and speed