Fig. 2: Microsynteny for OXT across PS 20–12.
From: An evolutionary timeline of the oxytocin signaling pathway
The ten genes surrounding OXT in the modern human build a microsyntenic block that is conserved across mammalian species. The synteny is less conserved in teleost fishes, as shown in the zebrafish microsyntenies for OXT and VT in two different loci (Zebrafish I and II), possibly due to a whole-genome duplication in the teleost fish ancestor134 that gave rise to genome reorganization events. The species' common names are given in the outer left column, followed by the corresponding PS and the microsyntenic block. Each rectangle represents one gene with the abbreviated gene name in the center. Gray, empty rectangles indicate a potential missing gene in that locus. Non-colored rectangles indicate no re-occurrence of a gene in the displayed species within microsyntenic distance. The microsyntenies for CD38 and OXTR are visualized in Supplementary Figs. 1 and 2. PS phylostratum, UP uncharacterized protein.
