Fig. 5: Smooth muscle cell and endothelial cell.
From: A single-cell atlas of lung homeostasis reveals dynamic changes during development and aging
a UMAP plots of smooth muscle cell (SMC) (left). Proportion of SMC subclusters in 3 groups (right). b Dot plots of specific marker genes of SMC. c Gene ontology enrichment analysis of gene expression in cluster 4 of VSMC (development). d Gene ontology enrichment analysis of gene expression in cluster 5 of VSMC (development). e UMAP plots of endothelial cell (EC) (left). Proportion of endothelial cell subclusters in 5 groups (right). f Dot plots of specific marker genes of endothelial cell. g Gene ontology enrichment analysis of gene expression in cluster 4 of capillary endothelial cell (development). h Gene ontology enrichment analysis of gene expression in cluster 6 of capillary endothelial cell (development). i Gene ontology enrichment analysis of up (top part, red)/down (bottom part, blue)-regulated gene expression in aging capillary endothelial cell. j The proliferative (GO: 0001935) scores and the apoptotic (GO: 0072577) scores of endothelial cells. The choice of ANOVA tests was based on the results of Shapiro–Wilk normality test. Dunnett tests were used to inter-group comparison.
