Fig. 3: A sub-screen identified huckebein (hkb) as a genetic interactor.
From: hkb is required for DIP-α expression and target recognition in the Drosophila neuromuscular circuit
a Cartoon depicting the deleted regions within deficiency lines ED5100, ED5142, and ED5046. b Quantification shows a significant reduction of m4-Is innervation when combining ED5046, but not ED5142, with the sensitized background, suggesting the shared region between the original deficiency line (ED5100) and ED5046 covers the candidate gene(s). N (NMJs) = 177, 196, 155 and 155. p values are indicated. c Quantification of sub-screen of individual genes from candidate region shown in (a). Alleles used to create triple-heterozygotes are, auxD128, abs00620, cpxMI00784, vps24EY04708, hkb2, contG5080, tub2, lostEY11645. Note that huckebein (hkb2) further reduced m4-Is innervation frequency. N (NMJs) = 177, 138, 62, 58, 29, 135, 39, 77, 78 and 57. p values are indicated.
