Fig. 5: Dietary emulsifiers promote metabolic disorders and induce intestinal microbiota dysbiosis.
From: Common dietary emulsifiers promote metabolic disorders and intestinal microbiota dysbiosis in mice
The study revealed that dietary emulsifiers lecithin, sucrose fatty acid esters, and carboxymethylcellulose (CMC) were found to disturb glucose-insulin homeostasis, while mono- and diglycerides (MDG) disrupted blood lipid levels and glucose homeostasis. Additionally, these emulsifiers caused imbalances in the gut microbiota. Notably, MDG further exacerbated the increase in gut-derived LPS levels in the bloodstream. These findings provide insights into the risks linked to the consumption of dietary emulsifiers through the lens of gut microbiota, and may prompt a reevaluation of existing food safety policies and regulations governing food production. Illustrations in this figure were created with Keynote.
