Fig. 4: The RNA-SM profile of TCGA cervical cancer.
From: Pan-cancer discovery of somatic mutations from RNA sequencing data
a The SMGs in cervical cancer, as identified with the RNA-SMs using dNdScv. Genes labeled in red were also identified from the DNA-SM analysis. b Counts of the RNA-SMs in PIK3CA across different protein domains. The positions of amino acids are displayed along the x-axis. c Counts of the SMs in PIK3CA that led to amino acid substitutions, as identified with the RNA-seq, WXS, and combined data. d Mutational signatures in cervical cancer, as identified from the RNA-SM data. These included DNA mismatch repair, APOBEC, Aging, and POLE.
