Fig. 3: Analyses FOXP4 expression and its function by overexpression. | Communications Biology

Fig. 3: Analyses FOXP4 expression and its function by overexpression.

From: Androgen-responsive FOXP4 is a target for endometrial carcinoma

Fig. 3

a, b Expression levels of FOXP4 mRNA (a) and protein (b). HEC59 cells were transfected with a FOXP4 overexpression vector. Cell proliferation (n = 6) (c), colony-forming ability (d), and tumor growth (n = 6) (e) were promoted in FOXP4(+) HEC59 cells. Bars show 200 µm (d) and 1 cm (e). In FOXP4-overtransfected PPP268 cells (f), tumor growth was also promoted (n = 6) (g, h). Bars show 1 cm (g). Statistical analysis was performed by the Mann–Whitney U test (a, c–e, h). Error bars represent standard error. *p < 0.05, **p < 0.01.

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