Fig. 4: Analyses FOXP4 function by knockdown.
From: Androgen-responsive FOXP4 is a target for endometrial carcinoma
FOXP4 in HEC50B cells was downregulated by shRNA (a, b). Although cell proliferation was not changed (n = 6) (c), wound-healing ability (n = 3) (d), colony-forming ability (e), and tumor growth (n = 10) (f) were decreased by FOXP4 knockdown. Bars show 1 cm (f). FOXP4 in PPP268 cells was also downregulated by shRNA (g). Tumor growth of FOXP4(–) PPP268 cells was decreased (n = 6) (h, i). Bars show 1 cm (h). Statistical analysis was performed by the ANOVA followed by the Dunnett test (a, c–f). Error bars represent standard error. *p < 0.05.
