Fig. 1: BPS exposure for 48 h caused excessive estrogen synthesis in SVOG cells. | Communications Biology

Fig. 1: BPS exposure for 48 h caused excessive estrogen synthesis in SVOG cells.

From: Bisphenol S causes excessive estrogen synthesis by activating FSHR and the downstream cAMP/PKA signaling pathway

Fig. 1

a T content (n = 9). b E2 content (n = 9). c E2/T ratio (n = 9). d CYP19A1 activity (n = 8). e Representative images of Western blotting for relative expression of CYP19A1. f Densitometric analysis of Western blotting for relative expression of CYP19A1 (n = 3) (g) CYP19A1 gene expression (n = 3). h Representative images of transmission electron microscope. The red line indicates width of endoplasmic reticulum, and the scale bar is 500 nm. i Quantitative analysis of width of endoplasmic reticulum (n = 21). Data are expressed as mean ± SD. * indicated a significant difference from the solvent control (0.01 < P < 0.05), and ** indicated a highly significant difference from the solvent control (P < 0.01).

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