Fig. 3: The trajectory of the total frequency of snowflake alleles through time.

New ACE2 and AIM44 mutant genotypes rapidly emerged within 10 days leading to the increase of snowflake frequencies. However, as more new genotypes emerged rapidly in the next 10 days, snowflake frequencies remained stable frequencies, indicating the competition among snowflake genotypes and frequency-dependent selection. Modeling of multicellular genotype evolutionary dynamics over 60 days of settling selection. The predicted model: frequency=0.766-0.771*exp(−0.194*time). R2 = 0.729.