Fig. 4: PCA score plots analysis results on the dataset of cell-averaged Raman spectra measured in living human cancer lines. | Communications Biology

Fig. 4: PCA score plots analysis results on the dataset of cell-averaged Raman spectra measured in living human cancer lines.

From: Label-free morpho-molecular phenotyping of living cancer cells by combined Raman spectroscopy and phase tomography

Fig. 4

By screening the first PCs through MLR, PCA score plots can be used to linearly separate human colon cancer cell types in the PCA space, based on their biochemistry. Sample size = 5 independent cells/phenotype. a The scatter matrix compares pair-wise the first 7 PCs, explaining 96% of the total dataset variance. Red dashed lines highlight pairs of the most significant PCs, namely, PC5 and PC7. Grey dashed lines identify the less significant PC, namely, PC2. b The entire set of significant PCs is represented in the 3D PCA space.

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