Table 1 Lead SNPs of GWAS significant loci in the combined analysis for patients with vertigo in Taiwan
From: A genome-wide association study identifies novel loci of vertigo in an Asian population-based cohort
SNP | Chr | Position | Gene | Minor allele | Stage | MAF (case, control) | OR | 95% CI | P valuea |
|---|---|---|---|---|---|---|---|---|---|
rs6450850 rs6859527 | 5 5 | 31,529,199 31,529,192 | DROSHA | T | 1 | (0.134, 0.184) | 0.690 | 0.642‒0.741 | 3.53 × 10−23 |
2 | (0.141, 0.185) | 0.727 | 0.667‒0.793 | 1.75 × 10−12 | |||||
Com | (0.137, 0.184) | 0.704 | 0.666‒0.744 | 2.90 × 10−33 | |||||
rs295402 | 19 | 23,334,765 | ZNF91 | G | 1 | (0.439, 0.400) | 1.175 | 1.118‒1.234 | 2.49 × 10−10 |
2 | (0.445, 0.406) | 1.171 | 1.103‒1.244 | 4.55 × 10−7 | |||||
Com | (0.442, 0.401) | 1.172 | 1.129‒1.218 | 2.03 × 10−15 | |||||
rs1234168883 | 5 | 17,221,364 | BASP1 | T | 1 | (0.026, 0.020) | 1.324 | 1.130‒1.550 | 5.65 × 10−4 |
2 | (0.030, 0.020) | 1.590 | 1.325‒1.907 | 1.31 × 10−6 | |||||
Com | (0.028, 0.020) | 1.428 | 1.268‒1.609 | 1.31 × 10−8 |
