Fig. 6: Time-resolved SAXS of TG2 with Ca2+ and LM11. | Communications Biology

Fig. 6: Time-resolved SAXS of TG2 with Ca2+ and LM11.

From: Distinct conformational states enable transglutaminase 2 to promote cancer cell survival versus cell death

Fig. 6

a Schematic of sample flow in the Kenics mixer. b The time-resolved Guinier Rg of TG2 mixed with 2 mM Ca2+ (black) increases faster in the presence of 50 μM LM11 (red). c The Guinier Rg of TG2 mixed with Ca2+ in the absence (black) or presence of 50 μM LM11 (red) suggests LM11 increases the sensitivity of TG2 to calcium.

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