Fig. 5: Three-dimensional structure diagram showing receptor and ligand docking. | Communications Biology

Fig. 5: Three-dimensional structure diagram showing receptor and ligand docking.

From: Mendelian randomization reveals potential causal relationships between cellular senescence-related genes and multiple cancer risks

Fig. 5

Crystal structures of acceptor and ligand complexes. The protein skeleton is a cartoon representation. Small molecular ligands are rod-like. a–d Three-dimensional stereogram showing DNMT3B bound to DB01262, CHEMBL109912, CHEMBL408017, and CHEMBL3916914 ligands. e Three-dimensional stereogram showing MAP2K1 bound to the DB14904 ligand. f–j Three-dimensional stereogram showing SREBF1 bound to DB11133, DB03756, CHEMBL278703, CHEMBL497499, and CHEMBL1087984 ligands.

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