Fig. 3: Simulated steady states under a range of glucose concentrations. | Communications Biology

Fig. 3: Simulated steady states under a range of glucose concentrations.

From: Metabolic regulation of mitochondrial morphologies in pancreatic beta cells: coupling of bioenergetics and mitochondrial dynamics

Fig. 3: Simulated steady states under a range of glucose concentrations.The alternative text for this image may have been generated using AI.

Steady-state values of (a) glyceraldehyde 3-phosphate (in µM), (b) pyruvate (in µM), (c) calcium (in µM), (d) cytosolic and mitochondrial NADH-to-NAD ratios, (e) ATP, ADP, and AMP (in µM), (f) the ATP-to-ADP ratio, (g) the mitochondrial membrane potential (in millivolts, mV), (h) the mitochondrial population in node degrees 1, 2, and 3, and (i) the average degree of nodes were compared under different glucose concentrations. The x-axis represents relative glucose concentrations, with 5 mM being 1X in the model simulation.

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