Table 1 Propensities of mitochondrial node reactions

From: Metabolic regulation of mitochondrial morphologies in pancreatic beta cells: coupling of bioenergetics and mitochondrial dynamics

Mitochondrial node reactions

Equation

Propensity

tip-to-tip fusion

\({X}_{1}+{X}_{1}{\to }^{{a}_{1}}{X}_{2}\)

\({a}_{1}({x}_{1})({x}_{1}-1)\)

tip-to-tip fission

\({X}_{1}+{X}_{1}{\leftarrow }^{{b}_{1}}{X}_{2}\)

\({b}_{1}({x}_{2})\)

tip-to-side fusion

\({X}_{1}+{X}_{2}{\to }^{{a}_{2}}{X}_{3}\)

\({a}_{2}({x}_{1})({x}_{2})\)

tip-to-side fission

\({X}_{1}+{X}_{2}{\leftarrow }^{{b}_{2}}{X}_{3}\)

\({b}_{2}({x}_{3})\)

tip-to-tip fission-fusion ratio

\({c}_{1}=\frac{{a}_{1}}{{b}_{1}}\)

 

tip-to-side fission-fusion ratio

\({c}_{2}=\frac{{a}_{2}}{{b}_{2}}\)

 
  1. a1, b1, a2, and b2 are the rate constants of the reactions, and x1, x2, and x3 are the numbers of nodes with degrees 1, 2, and 3, respectively. c1 and c2 are the ratios between the fusion and fission rates of the two reactions (tip-to-tip and tip-to-side). Reactions with a higher propensity have a greater probability of being chosen and performed.
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