Fig. 3: IL-1RA is upregulated in inflamed bPSC. | Communications Biology

Fig. 3: IL-1RA is upregulated in inflamed bPSC.

From: Inflammation impacts androgen receptor signaling in basal prostate stem cells through interleukin 1 receptor antagonist

Fig. 3: IL-1RA is upregulated in inflamed bPSC.

A Il1rn and Il1a (arrows) are among the most upregulated genes in the inflamed bPSC compared to naïve bPSC as analyzed with scRNA-seq. B Violin plots of Il1rn, Il1a and Il1r1 expression in naïve and inflamed bPSC. C qRT-PCR of Il1rn isoforms and Il1a in naïve and inflamed bPSC (Naïve, n = 3–4; Inflamed, n = 3–8). D Upregulation of IL-1RA protein is confirmed using ELISA with lysates collected from naïve or inflamed bPSC (Naïve or Inflamed, n = 4). Data presented in this figure are mean ± SEM.

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