Fig. 4: Description of states 4, 5, and 6. | Communications Biology

Fig. 4: Description of states 4, 5, and 6.

From: Disrupted working memory event-related network dynamics in multiple sclerosis

Fig. 4

Each box presents the spectral content of the states in panels a (for state 4), c (for state 5), and e (for state 6). The spectral content is described by the spectral mode associated with the state, the normalized (z-score) power spectral density (PSD) map, and the brain glass with the phase-coupling network with the connections surviving thresholding via GMM. Then, for each state, we report the event-related (ER) profiles in panels b (for state 4), d (for state 5), and f (for state 6). The event-related profiles of activation of each state are reported for the three WM load conditions (0, 1, and 2 back) target and distractor, separately. In each plot, the three ER profiles are colour-coded for the three groups (HC, MS B−, MS B+) and show the mean curve (bold line) and standard deviation (colour-coded shaded areas) across subjects. The black lines underneath the curves delineate the time points in which the ER waves related to the two groups involved in the comparison (HC vs MS B-, HC vs MS B+, MS B− vs MS B+) are significantly different (permutation test with TFCE, p < 0.025, number of permutations n = 1000, multiple comparison correction via maximum statistics across states and group comparisons).

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