Fig. 7: Enrichment of CTCF and RAD21 in SOBS/CTS double-mutant embryos. | Communications Biology

Fig. 7: Enrichment of CTCF and RAD21 in SOBS/CTS double-mutant embryos.

From: Identification of responsible sequences which mutations cause maternal H19-ICR hypermethylation with Beckwith–Wiedemann syndrome-like overgrowth

Fig. 7

ChIP-qPCR analysis of CTS1-4 in H19-ICRmSOC3/+ (n = 6) and WT (n = 4), H19-ICRmSOC4/+ (n = 7) and WT (n = 6), and H19-ICRΔC3,4/+ (n = 7) and WT (n = 5) embryos from 2 litters at 10.5 dpc, as performed using CTCF (a) and RAD21 (b) antibodies. White and red bars indicate the WT and mutant, respectively. Error bars indicate standard deviation. P-values are indicated (unpaired two-tailed t-test). ns; not significant.

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