Fig. 5: Co-expression transitions of neurological pathways across digestive tissues. | Communications Biology

Fig. 5: Co-expression transitions of neurological pathways across digestive tissues.

From: Integrating genetics and transcriptomics to characterize shared mechanisms in digestive diseases and psychiatric disorders

Fig. 5

The Sankey diagram displays the co-expression transitions of genes (or co-expression modules) associated with neurological pathways across digestive tissues. Each rectangle represents a gene co-expression module, with the size corresponding to the number of genes, and different colors indicating distinct functional enrichments. The connection degree of each module is visualized based on the number of shared genes between two modules. Neurological modules and their connections are colored in coral. Hub genes identified by MTAG are highlighted in each module, with red denoting genes ranking within the top 5% of the module, yellow indicating a rank between 5 and 10%, green for a rank between 10 and 20%, and black representing a rank greater than 20%.

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