Fig. 7: hsa_circ_0001599 binds to hnRNPA2B1 and promotes its translocation from the nucleus to the cytoplasm. | Communications Biology

Fig. 7: hsa_circ_0001599 binds to hnRNPA2B1 and promotes its translocation from the nucleus to the cytoplasm.

From: hsa_circ_0001599 promotes odontogenic differentiation of human dental pulp stem cells by increasing ITGA2 expression and stability

Fig. 7: hsa_circ_0001599 binds to hnRNPA2B1 and promotes its translocation from the nucleus to the cytoplasm.

a Western blot analysis of the total hnRNPA2B1 levels in each groups. b Effect of hsa_circ_0001599 on hnRNPA2B1 protein levels in the nucleus and cytoplasm. c Immunofluorescence results. d The SRAMP database was used to predict the m6A site of hsa_circ_0001599. e MazF assay was used to analyse the m6A modification level of hsa_circ_0001599 after mineralization. f MazF assay was used to analyse the m6A modification level of hsa_circ_0001599 after hnRNPA2B1 knockdown. a, b, e, f All data were presented as the mean ± SD. *P < 0.05, **P < 0.01, ***P < 0.001, ****P < 0.0001, ns: not significant, a, b, f n = 3 for each group, e n = 9, n = 7 for each group. c Scale bar, 50 μm.

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