Fig. 3: STZ-treated mice display early satiety and within-session meal consumption patterns skewed toward most preferred flavors.
From: Neuroeconomically dissociable forms of mental accounting are altered in a mouse model of diabetes
a Timeline. Dashed box indicates relevant time period for this figure: day 7. b, c Rewards earned within each 2.5 min bin across the session (b) in total earnings or (c) earnings split by flavor ranking. * in black near the VEH / STZ legend labels represents significant differences between VEH- and STZ-treated groups collapsing across time. * in black near individual time bins represents significant differences between groups at those times. Blue arrows indicate a main effect of time (e.g., satiety related changes across the session), with significance reported in blue. d Cumulative total rewards earned summed across the session. e Percentage of total session rewards earned split by flavor. f Tail vein blood glucose levels sampled immediately before and after day 7’s session. g Change in blood glucose from f post minus pre task. h Scatter plot of change in blood glucose from g against change in body weight measured immediately before and after day 7’s session. Gray dashed lines indicate 0 on both axes. Scatter plot of pre-task blood glucose from f against day 7’s end-of-session earns for i least and j most preferred flavors. Dots represent individual mice. Error bars represent ±1 SEM. Shading represents 95% confidence interval of linear fit.
