Fig. 5: STZ-treated mice develop unique decision-making policies in fundamentally distinct types of choices.
From: Neuroeconomically dissociable forms of mental accounting are altered in a mouse model of diabetes
a–d Offer zone (top) and wait zone (bottom) thresholds plotted (a, c) each day across the entire Restaurant Row paradigm or (b, d) split by flavor ranking collapsed across the 1–30 s epoch. Green (offer zone) and blue (wait zone) dashed staircase represent the maximum possible threshold for stepwise (top) or gradual (bottom) schedules. e, f Offer zone and wait zone thresholds within each 2.5 min bin across the session (data collapsed from entire 1–30 s epoch). Both schedules collapsed in e depicting all VEH- (top) or STZ-treated mice (bottom). Horizontal shaded bands represent offer zone threshold of 30 (green) or wait zone threshold of 9.s-13.5 (blue), corresponding to thresholds representing a strategy that would yield the maximum amount of total food as one type of optimal strategy, should animals ignore flavors, that was previously theoretically and empirically determined9. Analysis from e replotted and split by least and most preferred flavors in f for both schedules collapsed (left) or for all groups splitting flavor rankings (right). g Standard deviation of offer zone and wait zone thresholds calculated across the four flavors within each 2.5 min bin. h Standard deviation of the number of rewards earned calculated across the four flavor rankings within each 2.5 min bin. Shading in (a, c)/error bars represent ±1 SEM.
