Fig. 8: Restoring ad libitum access to food only affects re-evaluation decisions, differentially in VEH- vs. STZ-treated mice. | Communications Biology

Fig. 8: Restoring ad libitum access to food only affects re-evaluation decisions, differentially in VEH- vs. STZ-treated mice.

From: Neuroeconomically dissociable forms of mental accounting are altered in a mouse model of diabetes

Fig. 8: Restoring ad libitum access to food only affects re-evaluation decisions, differentially in VEH- vs. STZ-treated mice.

Number of laps run in the correct direction (a) and total rewards earned (b) comparing between when mice were food restricted vs. had unlimited access to regular chow in the home cage (purple outlines). c Rewards earned split by flavor rankings. Offer zone thresholds (d) and wait zone thresholds (e) split by flavor ranking. Note no change in offer zone thresholds but a bidirectional change in wait zone thresholds (VEH: decreased; STZ: increased). f Normalized vicarious trial and error (VTE) behavior split by flavor ranking and by skip vs. enter offer zone outcomes. g Sensitivity to sunk cost delta curves plotted as a function of time already spent in the wait zone. Note abolished sunk costs in both STZ-treated groups regardless of schedule, in spite of no change in offer zone thresholds and similar shifts in wait zone thresholds. Insets depict peak scores. Horizontal dashed gray line represents 0. Shading/error bars represent ±1 SEM.

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