Fig. 4: Analysis of the post-mortem degradome. | Communications Biology

Fig. 4: Analysis of the post-mortem degradome.

From: A multi-tissue longitudinal proteomics study to evaluate the suitability of post-mortem samples for pathophysiological research

Fig. 4

a Concept of protein degradation post-mortem. b Number of significantly changing peptides post-mortem classified into their cleavage specificity. c Volcano plot highlights differentially abundant peptides in the spleen between fresh samples (group 1) and samples incubated for 4 days. d Semi-tryptic cleave motif enrichment analysis, reveals specific and time-dependent cleavage motifs. P values were calculated using a two-sided Student t-test using equal variance and a p < 0.05 was considered as significant. N = 5 for all mouse proteomics samples.

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