Fig. 3: Whole genome sequencing analysis demonstrated a large proportion of EV DNA molecules from non-coding regions of the genome. | Communications Biology

Fig. 3: Whole genome sequencing analysis demonstrated a large proportion of EV DNA molecules from non-coding regions of the genome.

From: EV DNA from pancreatic cancer patient-derived cells harbors molecular, coding, non-coding signatures and mutational hotspots

Fig. 3

A Schematic diagram of the size selection. Following the sequencing of the DNA from the EVs (isolated by the kit-based method), the reads were re-aligned against the human genome, the percentage of reads from the high (B) or low (C) molecular weight fraction mapping to the coding or non-coding regions was determined bioinformatically, and graphed. D Average of the reads mapping to coding vs. non-coding regions from all ten cell lines.

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